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Symbol Name ID |
Map2k1
mitogen-activated protein kinase kinase 1 MGI:1346866 |
| Darker colors indicate more annotations |
| Human Phenotypes | Atrial septal defect |
Ventricular septal defect |
Hypertrophic cardiomyopathy |
Pulmonic stenosis |
| Disease(s) Associated with MAP2K1 | ||||
| cardiofaciocutaneous syndrome 3 |
| Mouse Phenotypes | pulmonary artery stenosis |
abnormal placental labyrinth vasculature morphology |
abnormal angiogenesis |
abnormal vascular endothelial cell migration |
increased myocardial fiber size |
heart left ventricle hypertrophy |
increased heart weight |
thick ventricular wall |
abnormal cardiac output |
decreased left ventricle diastolic pressure |
increased left ventricle systolic pressure |
decreased cardiomyocyte apoptosis |
decreased myocardial infarct size |
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| Availability | Mouse Genotype | |||||||||||||
| Map2k1Gt(ROSABetageo)J2Chrn/Map2k1Gt(ROSABetageo)J2Chrn | ||||||||||||||
| Map2k1tm2.1Chrn/Map2k1tm2.1Chrn | ||||||||||||||
| Map2k1tm2.1Chrn/Map2k1+ | ||||||||||||||
| Map2k1tm2.1Chrn/Map2k1tm1.1Chrn | ||||||||||||||
| Tg(Myh6-Map2k1*)1Jmol/? | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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